Original Lotus Itra Fragrance should be applied to pulse points. This is where the blood vessels are closest to the skin giving off more heat and acting like mini fragrance pumps. Pulse points are the wrist, behind the ear, crook of the arm and knee, base of the throat. Also, for long lasting fragrance at the ankles, it allows the fragrance to blossom up. Use fragrance throughout every day. Different scents are believed to have their own unique affect on mood and feeling. Always remember to keep your fragrances safe from extreme cold or heat.